Barend Mons is Professor of BioSemantics at the Human Genetics Department of Leiden University Medical Center and founder of the BioSemantics group. Next to his leading role in the research of the group, Barend plays a leading role in the international development of "data stewardship" for biomedical data. For instance, he was head-of-node of ELIXIR-NL at the Dutch Techcentre for Life Sciences (until 2015), is Integrator Life Sciences at the Netherlands eScience Center, and board member of the Leiden Centre of Data Science. In 2014, Barend initiated the FAIR data initiative and in 2015, he was appointed Chair of the European Commission's High Level Expert Group for the "European Open Science Cloud", from which he retired by the end of 2016. Presently, Barend is co-leading the GO FAIR initiative, an initiative to kick start developments towards the Internet of FAIR data and services, which will also contribute to the implementation of components of the European Open Science Cloud. The focus of the contribution of the BioSemantics group is on developing an interoperability backbone for biomedical applications in general and rare disease in particular.